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Tim Eubank, Ph.D.
Research Scientist
201 Davis Heart & Lung Research Institute
473 West 12th Avenue
Columbus, OH 43210
(614) 366-1332
Education:
2003 Ph.D. The Ohio State Biochemistry Program, The Ohio State University
Mentor: Clay B. Marsh, MD
Research Interests:
Mechanisms of breast cancer growth and metastases
Awards and Honors:
2007 Outstanding Poster, Faculty/Research Scientist Division, 2nd Annual Pulmonary Research Day
2006 Chief Post-doctoral Fellow, the Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine
2005 Davis Heart & Lung Research Institute Distinguished Post-Doctoral Researcher of the Year
Grant Awards:
Current: NIH/NCI 1 K99 CA131552-01
K99/R00 Pathway to Independence Role: PI
Current: NIH/NCI 1R21CA132068-01 Role: Co-I
Completed: OSU DHLRI Internal Funding Role: PI
Completed: NIH/NHLBI T32 HL07946-01 Wewers (PI) Role: Fellow
Publications:
1. Eubank TD and Roberts RD, Khan M, Curry JM, Nuovo GJ, Kuppusamy P, and Marsh CB. GM-CSF inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages. Cancer Research. 2008 (In press).
2. Hunter M, Wang Y, Eubank TD, Baran CP, Nan-Sinkham P, Marsh CB. Myeloid Cell Survival and its Role in Health and Disease. Frontiers in Bioscience. 2008 (In press).
3. Curry JM and Eubank TD, Roberts RD, Wang Y, Pore N, Maity A, Marsh CB. M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo. PLoS ONE. 2008 (In press).
4. Bringardner BD, Baran CP, Eubank TD, Marsh CB. The Role of Inflammation in the Pathogenesis of Idiopathic Pulmonary Fibrosis. Antioxid Redox Signal. 2007 Volume 10, Number 2.
5. Parinandi NL, Sharma A, Eubank TD, Kaufman BF, Kutala VK, Marsh CB, Ignarro LJ, Kuppusamy P. Nitroaspirin (NCX-4016), an NO Donor, ia Antiangiogenic Through Induction of Loss of Redox-Dependant Viability and Cytoskeletal Reorganization in Endothelial Cells. Antioxid Redox Signal. 2007 Aug 30.
6. Wang Y, Zeigler MM, Lam GK, Hunter MG, Eubank TD, Khramtsov VV, Tridandapani S, Sen CK, Marsh CB. The Role of the NADPH Oxidase Complex, p38 MAPK and Akt in Regulating Human Monocyte/Macrophage Survival. Am J Respir Cell Mol Biol. 2007 Jan;36(1):68-77.
7. Yang EV, Sood AK, Chen M, Yeh P, Eubank TD, Marsh CB, Jewell S, Flavahan NA, Morrison C, Glaser R. Norepinephrine up-regulates the expression of VEGF, MMP-2 and MMP-9 in nasopharyngeal carcinoma tumor cells. 2006. Cancer Research, Nov 1;66(21):10357-64.
8. Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB. GM-CSF Induces Expression ofSoluble VEGF Receptor-1 from Human Monocytes and Inhibits Angiogenesis in Mice. 2004. Immunity, 21:831-842.
9. Eubank TD, Galloway M, Montague CM, Waldman WJ, Marsh CB. M-CSF induces vascular endothelialgrowth factor production and angiogenic activity from human monocytes. 2003. The Journal of Immunology, 171: 2637-2643.
10. Eubank TD, Biswas R, Jovanovic M, Litovchick A, Lapidot A, Gopalan V. Inhibition of bacterial RNase Pby aminoglycoside-arginine conjugates. 2002. FEBS Letters, 511: 107-12.
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